10 Great Chemistry Gift Ideas: A Guide for Science Lovers
Finding the perfect gift for a chemist can be a bit of a challenge. Here’s a list of 10 great gifts to delight the chemist in your life.
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the-chemistry-editor
Aug 233 min read
Baldwin's Rules: Predicting the Outcome of Ring-Closing Reactions
Baldwin's Rules, introduced by Jack Baldwin in 1976, are guidelines for predicting the favorability of ring-closing reactions.
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the-chemistry-editor
Jul 185 min read
Measuring Steric Impact: Understanding 'A Values'
How do we compare the steric demand of different substituents? One method is to consider their 'A values', derived from cyclohexane studies.
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the-chemistry-editor
Jul 103 min read
The Rise of PROTACs in Medicinal Chemistry
PROTACs bring together a target protein and an E3 ligase. The protein is then selectively ubiquitinated and degraded by the proteasome.
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the-chemistry-editor
Jun 284 min read
Mosher's Esters: A Key Tool in Stereochemical Analysis
Mosher’s acids are chiral derivatizing agents that react with chiral alcohols to form Mosher’s esters and enable stereochemical analysis.
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the-chemistry-editor
Jun 183 min read
The Chiral Pool: Harnessing Nature's Chirality
The chiral pool refers to a collection of readily available, naturally occurring chiral molecules, such as amino acids, sugars and terpenes.
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the-chemistry-editor
Jun 43 min read
Ellman’s Sulfinamide Auxiliaries in the Synthesis of Chiral Amines
Ellman's tert-butylsulfinamides were introduced by Jonathan A. Ellman in 1997 as a chiral auxiliary for the synthesis of enantiopure amines.
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the-chemistry-editor
May 201 min read
The Fürst-Plattner Rule: Regioselective Epoxide Opening
The Fürst-Plattner rule allows us to predict the regio- and stereochemical outcome of epoxide-opening reactions on six-membered rings.
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the-chemistry-editor
May 161 min read
The Staudinger Reaction: Conversion of Azides into Amines
The Staudinger reaction is a useful reaction that involves the reduction of an azide to an amine using triphenylphosphine.
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the-chemistry-editor
Apr 302 min read
The Mitsunobu Reaction in Organic Synthesis
The Mitsunobu reaction is a convenient method for the conversion of alcohols into esters, aryl ethers, azides, sulfonamides and sulfides.
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the-chemistry-editor
Mar 103 min read
Stereoselective Allylation with Allylsilanes: The Hosomi–Sakurai Reaction
Whereas allylations involving allylboron reagents are Type I allylations, the Hosomi–Sakurai reaction is an example of a Type II
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the-chemistry-editor
Feb 241 min read
Stereoselective Allylation with Allylboron: Roush and Brown Reagents
Allylations involving allylboron reagents are often highly stereoselective, owing to a Zimmerman-Traxler-like cyclic transition state.
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the-chemistry-editor
Feb 182 min read
The Chemistry of Oxytocin – The "Love Hormone"
Within the intricate web of human emotions and connections, there exists a tiny yet powerful molecule known as oxytocin. Often dubbed the...
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the-chemistry-editor
Feb 171 min read
COX Inhibitors: The Chemistry of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
Nonsteroidal anti-inflammatory drugs (NSAIDs) are a class of medications used to alleviate pain, reduce inflammation and lower fever.
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the-chemistry-editor
Feb 86 min read
The History of Swern and Related 'Activated DMSO' Oxidations
In 1978, Daniel Swern and Kanji Omura published their paper introducing the Swern Reaction, the most popular 'activated DMSO' oxidation.
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the-chemistry-editor
Jan 92 min read
Unearthing Clovibactin: A Breakthrough Depsipeptide Antibiotic Defying Drug Resistance
The potent depsipeptide antibiotic clovibactin defies drug resistance. It is sourced from previously uncultivated soil bacteria.
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the-chemistry-editor
Sep 20, 20232 min read
Homophones, Homographs, Homonyms and Heteronyms: What's the Difference?
Homophones, homographs, homonyms and heteronyms arise when words that sound or look alike have different meanings.
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the-chemistry-editor
Sep 12, 20232 min read
From the Archives: Crouch's 'Selective Monodeprotection of Bis-silyl Ethers'
An indispensable reference guide for planning synthetic pathways that require the strategic use of silyl protecting groups.
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the-chemistry-editor
Sep 7, 20232 min read
Supramolecular Peptide Hydrogels: A Revolution in Drug Delivery Systems
Supramolecular peptide hydrogels are a class of hydrogels formed through non-covalent interactions between peptide molecules.
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the-chemistry-editor
Sep 1, 20232 min read
Fewer vs. Less: Quantifiable vs. Unquantifiable Nouns
The English language is full of rules and exceptions. An example that often leaves people puzzled is the choice between "less" and "fewer."
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