Mosher’s acids are chiral derivatizing agents that react with chiral alcohols to form Mosher’s esters and enable stereochemical analysis.

The chiral pool refers to a collection of readily available, naturally occurring chiral molecules, such as amino acids, sugars and terpenes.

Ellman's tert-butylsulfinamides were introduced by Jonathan A. Ellman in 1997 as a chiral auxiliary for the synthesis of enantiopure amines.

The Fürst-Plattner rule allows us to predict the regio- and stereochemical outcome of epoxide-opening reactions on six-membered rings.

The Staudinger reaction is a useful reaction that involves the reduction of an azide to an amine using triphenylphosphine.

The Mitsunobu reaction is a convenient method for the conversion of alcohols into esters, aryl ethers, azides, sulfonamides and sulfides.

Whereas allylations involving allylboron reagents are Type I allylations, the Hosomi–Sakurai reaction is an example of a Type II

Within the intricate web of human emotions and connections, there exists a tiny yet powerful molecule known as oxytocin. Often dubbed the...

In 1978, Daniel Swern and Kanji Omura published their paper introducing the Swern Reaction, the most popular 'activated DMSO' oxidation.

The potent depsipeptide antibiotic clovibactin defies drug resistance. It is sourced from previously uncultivated soil bacteria.

A tool in the arsenal of nearly every organic chemist, Nudelman's paper has been the go-to guide for NMR analysis for over 25 years.

In the summer of 2022, two syntheses of darobactin A were reported within a week of each other; the first by Sarlah, the second by Baran.